Publications

Buckup M, Figueiredo I, Ioannou, …, Roudko V, Gonzalez-Kozlova E, Hamon P, Merad M, Gnjatic S. Multiparametric cellular and spatial organization in cancer tissue lesions with a streamlined pipeline. Nat Biomed Eng 2025

Pravin Patel et al, …, Haymaker CL, Kurzrock R. Immunological biomarkers of response and resistance to treatment with cabozantinib and nivolumab in recurrent endometrial cancer. J Immunother Cancer. 2025

Roudko V, Del Valle DM, …, Gnjatic S. Immunological biomarkers of response and resistance to treatment with cabozantinib and nivolumab in recurrent endometrial cancer. J Immunother Cancer. 2025

Wen PY, et al., A multi-institutional phase 1 clinical trial exploring upfront multimodal standard of care and combined immunotherapies for newly diagnosed glioblastoma. Neuro Oncol. 2025

Jayaraman P, et al., Peripheral Transcriptomics in Acute and Long-Term Kidney Dysfunction in SARS-CoV2 Infection. Kidney360. 2025

Shang J, et al., Baseline colitogenicity and acute perturbations of gut microbiota in immunotherapy-related colitis. J Exp Med. 2025

Miceli RT, …, Gonzalez-Kozlova E, Dogra N. Extracellular vesicles, RNA sequencing, and bioinformatic analyses: Challenges, solutions, and recommendations. J Extracell Vesicles. 2024

Bao R, …, Meerzaman D, Liu S, Van Allen EM, Xing Y. Ten challenges and opportunities in computational immuno-oncology. J Immunother Cancer. 2024

Cappuyns S, …, Villanueva A, Dekervel J, Llovet JM. Single-cell RNA seq-derived signatures define response patterns to atezolizumab + bevacizumab in advanced hepatocellular carcinoma. J Hepatol. 2024

Espada CE, et al., ISG15/USP18/STAT2 is a molecular hub regulating IFN I-mediated control of Dengue and Zika virus replication. Front Immunol. 2024

Monette A, …, Gonzalez-Kozlova E, Tirosh I, Wang X, Gnjatic S. The Society for Immunotherapy of Cancer Perspective on Tissue-Based Technologies for Immuno-Oncology Biomarker Discovery and Application. Clin Cancer Res. 2024

Archer M, Begemann D, Gonzalez-Kozlova E, Nepali PR, Labanca E, Shepherd P, Dogra N, Navone N, Kyprianou N. Kinesin Facilitates Phenotypic Targeting of Therapeutic Resistance in Advanced Prostate Cancer. Mol Cancer Res. 2024

Dogra N*, Chen TY*, Gonzalez-Kozlova E*, Miceli R, Cordon-Cardo C, Tewari AK, Losic B, Stolovitzky G. Extracellular vesicles carry transcriptional dark matter revealing tissue-specific information. J Extracell Vesicles. 2024 *contributed equally.

Gonzalez-Kozlova E, Huang HH, Jegede OA, Tuballes K, Del Valle DM, …, Kim-Schulze S, Diefenbach CS, Gnjatic S. Tumor-immune signatures of treatment resistance to brentuximab vedotin with ipilimumab and/or nivolumab in Hodgkin lymphoma. Cancer Res. Commun. 2024

Parra ER*, Zhang J*, Duose DY*, Gonzalez-Kozlova E*, Redman MW, …, Gnjatic S, Lee JJ, Zhang J, Haymaker C. Multi-omics analysis reveals immune features associated with immunotherapy benefit in squamous cell lung cancer patients from Phase III Lung-MAP S1400I trial. Clin Cancer Res. 2024 *contributed equally.

LaMarche NM et al., An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis. Nature. 2024

Galsky MD, Daneshmand S, Izadmehr S, Gonzalez-Kozlova E, …, Gnjatic S, Sfakianos J, Pal SK. Gemcitabine and cisplatin plus nivolumab as organ-sparing treatment for muscle-invasive bladder cancer: a phase 2 trial. Nat Med. 2023.

Soleymani T.*, Chen T.*, Gonzalez-Kozlova E., Dogra N. The human neurosecretome: extracellular vesicles and particles (EVPs) of the brain for intercellular communication, therapy, and liquid-biopsy applications. Frontiers in Molecular Biosciences 2023. *contributed equally.

Coffey DG., Maura F., Gonzalez-Kozlova E., …, Gnjatic S., Landgren O. Immunophenotypic correlates of sustained MRD negativity in patients with multiple myeloma. Nature Communications 2023. *contributed equally.

Pilcher W., Thomas BE., Bhasin SS., Jayasinghe RG., Yao L., Gonzalez-Kozlova E., …, Gnjatic S., Ding L., Bhasin M. Cross center single-cell RNA sequencing study of the immune microenvironment in rapid progressing multiple myeloma. npj genomic medicine 2023.

Su CY*., Zhou S*., Gonzalez-Kozlova E*., …, Gnjatic S., Kaufmann D., Merad M. Circulating proteins to predict COVID‐19 severity Scientific Reports 2023. *contributed equally.

Magen A., …, Gonzalez-Kozlova E., …, Gnjatic S., …, Merad M. Intratumoral dendritic cell–CD4+ T helper cell niches enable CD8+ T cell differentiation following PD-1 blockade in hepatocellular carcinoma. Nature Medicine 2023.

Li X.*, La Salvia S.*, Liang Y.*, …, Gonzalez-Kozlova E., Dubois N, Dogra N., Hajjar R., Sahoo S. Extracellular Vesicle–Encapsulated Adeno-Associated Viruses for Therapeutic Gene Delivery to the Heart. Circulation 2023. *contributed equally.

Chen TY*, Gonzalez-Kozlova E*, Soleymani T, La Salvia S, Kyprianou N, Sahoo S, Tewari AK, Cordon-Cardo C, Stolovitzky G, Dogra N. Extracellular vesicles carry distinct proteo-transcriptomic signatures that are different from their cancer cell of origin. iScience 2022. *contributed equally.

Gonzalez-Kozlova E. Molecular Profiling of Liquid Biopsies for Precision Oncology. Adv Exp Med Biol 2022.

Aranda CJ*, Gonzalez‐Kozlova E*, Saunders SP, …, Guttman‐Yassky E, Curotto de Lafaille MA. IgG memory B cells expressing IL4R and FCER2 are associated with atopic diseases. Allergy 2022. *contributed equally.

Thompson RC, Simons NW, Wilkins L, …, Edgar Gonzalez-Kozlova, Boyman O, Kim-Schulze S, Sebra R, Merad M, Gnjatic S, Schadt EE, Charney AW & Beckmann ND. Molecular states during acute COVID-19 reveal distinct etiologies of long-term sequelae. Nat Med 2022.

Carbonell G*, Del Valle MD*, Gonzalez-Kozlova E*, …, Gnjatic S, Taouli B. Quantitative chest computed tomography combined with plasma cytokines predict outcomes in COVID-19 patients. Heliyon 2022. *contributed equally.

Butler-Laporte G*, Gonzalez-Kozlova E*, Su CY, Zhou S, …, Gnjatic S, Richards JB. The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals. Clin Proteomics 2022. *contributed equally.

Medina-Santos R, Fernandes Costa TG, Silva de Assis TC, Kalapothakis Y, de Almeida Lima S, do Carmo AO, Gonzalez-Kozlova E, Kalapothakis E, Chávez-Olórtegui C, Guerra-Duarte C. Analysis of NGS data from Peruvian Loxosceles laeta spider venom gland reveals toxin diversity. Comp Biochem Physiol Part D Genomics Proteomics 2022.

Gaglani S, Gonzalez-Kozlova E, Lundon DJ, Tewari AK, Dogra N, Kyprianou N. Exosomes as A Next-Generation Diagnostic and Therapeutic Tool in Prostate Cancer. Int J Mol Sci. 2021.

von Felden J, Garcia-Lezana T, Dogra N, Gonzalez-Kozlova E, …, Stolovitzky G, Losic B, Villanueva A. Unannotated small RNA clusters associated with circulating extracellular vesicles detect early stage liver cancer. Gut. 2021.

Hernandez-Meza G, von Felden J, Gonzalez-Kozlova E, …, Gnjatic S, Merad M, Rahman AH. DNA Methylation Profiling of Human Hepatocarcinogenesis. Hepatology. 2021.

Geanon D, Lee B, Gonzalez-Kozlova E, …, Gnjatic S, Merad M, Rahman AH. A streamlined whole blood CyTOF workflow defines a circulating immune cell signature of COVID-19. Cytometry A. 2021.

Bubie A, Gonzalez-Kozlova E, …, Akers N, Villanueva A, Losic B. Tumor fitness, immune exhaustion and clinical outcomes: impact of immune checkpoint inhibitors. Sci Rep. 2020.

Gonzalez-Kozlova E, Cerf L, … Felicori L, Chávez-Olórtegui C, Machado-de-Ávila RA. Computational B-cell epitope identification and production of neutralizing murine antibodies against Atroxlysin-I. Sci Rep. 2018.

Gonzalez-Kozlova E, Viart B, de Avila R, Felicori L, Chavez-Olortegui C. Classification epitopes in groups based on their protein family. BMC Bioinformatics. 2015.